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Primary mediastinal large B‐cell lymphoma (PMBCL) is a rare aggressive B‐cell lymphoma characterized by the frequent presence of amplification and translocation events at 9p24.1, resulting in the expression of the programmed cell death‐1 (PD‐1) ligands PD‐L1 and PD‐L2. Pembrolizumab, a humanized anti‐PD‐1 monoclonal antibody, binds PD‐1 and blocks this interaction, enhancing the activity of the immune...
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