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Introduction: The first heart sound (S1) carries information about ventricular function which may be clinically useful in optimization of cardiac resynchronization therapy (CRT). We developed a method of measuring the effects of CRT on S1 energy.
Traditional apex-cardiography measures chest wall vibrations at the apex beat using an air-coupled microphone. To provide additional insight in apex-cardiography and chest vibrations we estimated the three dimensional displacement of the apex beat.
Early repolarization (ER) in the inferior/lateral leads of 12-lead ECG increases the risk of arrhythmic death. Automatic methods are needed to robustly locate the J-point in ER positive ECGs so large databases with electrocardiographic ER patterns can be analyzed.
Drugs that prolong the QTc interval to clinically relevant magnitudes are likely to be proarrhythmic if they also produce relevant changes in the morphology of repolarization waveforms. Concurrent analyses of QTc and the T-wave Morphology Combination Score (MCS) have already shown how this approach can improve characterization of repolarization effects for a number of drugs. In this study we develop...
Renal Artery Stenosis (RAS) is the most common cause of secondary hypertension, and early diagnosis is important since correct and timely treatment may cure hypertension and prevent loss of renal function. This study investigates a new approach to diagnosing renal artery stenosis by computer analysis of the phonogram recorded with an electronic stethoscope. Phonograms recorded from five positions...
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