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A growing body of evidence has proved that the expression of COL1A2 is associated with a reduced risk of osteoporotic fracture. One single‐nucleotide polymorphism (rs3917) located within the 3′‐untranslated region of COL1A2 may “alter” binding site of miR‐382 and thereby associated with the risk of osteoporotic fracture. Bioinformatic analysis, luciferase reporter assay, site‐directed mutagenesis,...
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