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Kashin–Beck disease (KBD) is a chronic degenerative osteoarthropathy with unclear etiology. To provide current evidence supporting a genetic predisposition for KBD, we conducted a systematic review and meta-analysis of published literature on the genetic epidemiology of KBD. The PubMed, China National Knowledge Infrastructure and Wan Fang Data were searched up to August 2015 for articles published...
Kashin-Beck disease (KBD) is a chronic, endemic osteochondropathy in China. cDNA microarray techniques were used to select the differentially expressed genes between the healthy and KBD patients. 227 differently expressed genes were used to identify common characteristics. By using GeneMerge anaysis, the common functions of these genes were identified and some of which are related to metal ion binding,...
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