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Age‐related bone defects are a leading cause of disability and mortality in elderly individuals, and targeted therapy to delay the senescence of bone marrow‐derived mesenchymal stem cells (MSCs) has emerged as a promising strategy to rejuvenate bone regeneration in aged scenarios. More specifically, activating the nicotinamide adenine dinucleotide (NAD+)‐dependent sirtuin 1 (SIRT1) pathway is demonstrated...
Assembled heterostructure systems, as emerging functional materials, have broad applications ranging from enzyme and drug payload to catalysis and purification. However, these require trial‐ and ‐error design process and complex experimental environment to generate heterostructure materials. Here, this study describes an easy‐to‐execute strategy to fabricate magnetic heterostructure as multifunctional...
Electrochemical bioassays based on oxidase reactions are frequently used in biological sciences and medical industries. However, the enzymatic reaction kinetics are severely restricted by the poor solubility and slow diffusion rate of oxygen in conventional solid‒liquid diphase reaction systems, which inevitably compromises the detection accuracy, linearity, and reliability of the oxidase‐based bioassay...
The efficient storage of electrons and the type of conduction in semiconductor materials are important factors in determining their electrochemical performance. However, the interaction between these two factors is often overlooked by researchers. In this study, the effects of Ni doping at Co3−xNixO4 nanoparticles on the electronic storage form of the material and resulting changes in the conduction...
Water‐responsive (WR) materials that reversibly deform in response to relative humidity (RH) changes are gaining increasing interest for their potential in energy harvesting and soft robotics applications. Despite progress, there are significant gaps in the understanding of how supramolecular structure underpins the reconfiguration and performance of WR materials. Here, three crystals are compared...
Li||NMC811 battery, with lithium‐metal (high specific capacity and low redox potential) as anode and LiNi0.8Co0.1Mn0.1O2 (NMC811) as cathode, has been widely accepted to be a good candidate as one of the high‐energy‐density batteries. However, its cyclability needs improvement to fulfill the requirement for its future commercial use, especially under practical conditions. Electrolyte plays a key role...
Enhanced electrochemiluminescence (ECL) aims to promote higher sensitivity and obtain better detection limit. The core–shell nanostructures, owing to unique surface plasmon resonance (SPR) enabling distance‐dependent strong localized electromagnetic field, have attracted rising attention in enhanced ECL research and application. However, the present structures usually with porous shell involve electrocatalytic...
The development of programmable functional biomaterials makes 4D printing add a new dimension, time (t), based on 3D structures (x, y, z), therefore, 4D printed constructs could transform their morphology or function over time in response to environmental stimuli. Nowadays, highly efficient bone defect repair remains challenging in clinics. Combining programmable biomaterials, living cells, and bioactive...
Platinum‐based atomically ordered alloys (i.e., intermetallic compounds) have distinct advantages over disordered solid solution counterparts in boosting the cathodic oxygen‐reduction reaction (ORR) in proton‐exchange‐membrane fuel cells. Nevertheless, the pivotal role of ordering degree of intermetallic catalysts in promoting ORR performance has been ignored heavily so far, probably owing to the...
Temperature sensing based on fluorescent semiconductor nanocrystals has recently received immense attention. Enhancing the trap‐facilitated thermal quenching of the fluorescence should be an effective approach to achieve high sensitivity for temperature sensing. Compared with conventional semiconductor nanocrystals, the defect‐tolerant feature of lead halide perovskite nanocrystals (LHP NCs) endows...
Increased applications of nanoporous graphene in nanoelectronics and membrane separations require ordered and precise perforation of graphene, whose scalablility and time/cost effectiveness represent a significant challenge in existing nanoperforation methods, such as catalytical etching and lithography. A strain‐guided perforation of graphene through oxidative etching is reported, where nanopores...
Mucin 1 (MUC1) peptide fused with Q11 (MUC1‐Q11) having 35 residues has previously been shown to form amyloid fibrils. Using time‐dependent and high‐resolution atomic force microscopy (AFM) imaging, it is revealed that the formation of individual MUC1‐Q11 fibrils entails nucleation and extension at both ends. This process can be altered by local mechanical perturbations using AFM probes. This work...
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