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Objective To test the effects of high-frequency percussive ventilation (HFPV) compared with high-frequency oscillatory ventilation (HFOV) and low-volume conventional mechanical ventilation (LVCMV), on lung injury course in a gastric juice aspiration model. Design Prospective, randomized, controlled, in-vivo animal study. Setting University animal research laboratory. Subjects Forty-three New...
Objective To characterize hemodynamic changes during experimental aspiration pneumonitis, paying special attention to echocardiographic assessment. Design and setting Animal study in a university-based research laboratory. Subjects Fourteen mechanically ventilated New Zealand white rabbits Interventions We instilled 1 ml/kg human gastric juice (mean pH: 4.1 + 0.2) intratracheally. Hemodynamic...
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