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Endothelial dysfunction is fundamental to ischemic stroke and brain injury. The humanin analogue S14G‐humanin (HNG) has been shown to be a cytoprotective derivative. In this study, we investigated the neuroprotective effects of HNG in vivo and in vitro. In a murine middle cerebral artery occlusion (MCAO) stroke model, HNG ameliorates cerebral infarction and suppresses the production of TNF‐α, IL‐1β,...
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