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A substantial number of colon cancer patients do not benefit from immunotherapy using programmed cell death 1 (PD1) antibodies. Therefore, combination therapy drugs are required to improve the efficacy of colon cancer immunotherapy. Recent studies have shown that deubiquitinases are negative regulators of anti‐tumour immunity. In the present study, we investigated the effect of the deubiquitinase...
β‐Arrestins are well‐known regulators and mediators of G protein‐coupled receptor signalling, and accumulating evidence reveals that they are functionally involved in inflammation and autoimmune diseases. Of the two β‐arrestins, β‐arrestin 1 is documented to play regulatory roles in an animal model of multiple sclerosis (MS), whereas the role of β‐arrestin 2 is less clear. Here, we show that β‐arrestin...
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