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ObjectiveTo investigate the effect of cartilage on nucleus pulposus (NP) tissue in an in vitro model.
MethodsCells were isolated from bovine NP or articular cartilage and allowed to form tissue in vitro. The NP tissue was grown either alone or in the presence of cartilage tissue (coculture) for up to 4 weeks and examined for histologic appearance, gene expression, and biochemical composition. For...
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