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Achilles tendon injuries are common clinical problems for athletes, especially in runners. Several studies indicate that Achilles tendinopathy is accompanied with neovascularization or hypervascularity; thus, assessments of vascularity are important when assessing inflammation changes in tendon injuries. Photoacoustic imaging, taking the advantages of good ultrasonic resolution and high optical absorption...
In this study, we propose a radial-modulation chirp imaging method for contrast detection with high frequency ultrasound. This method detects microbubbles by extracting and then selectively compressing the radial-modulated chirp component of the response. The amplitude of the imaging chirp signal will be radial modulated at the resonance frequency due to the high-amplitude oscillation of the microbubble...
Contrast-assisted techniques that quantitatively estimate time-intensity curves (TICs) within the perfusion area have been applied in many disease models. In this study, we monitored the microbubble replenishment by a proposed new approach called the time-Nakagami-parameter curve (TNC) obtained from Nakagami-parameter images for quantifying the microvascular flow velocity. The feasibility of using...
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