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Objective Our study aimed to evaluate the effectiveness of an 8-week stress management intervention program that included progressive muscle relaxation, diaphragmatic breathing, guided imagery, and cognitive restructuring in obese Greek children and adolescents. Design Thirty-six patients were prospectively recruited to participate in this randomized controlled study. Of these, 16 participants formed...
Pediatric and adolescent obesity commonly coexist with stress‐related symptoms and disorders. Stress, the state of threatened homeostasis, is associated with the acute activation of the hypothalamic–pituitary–adrenal axis and the sympathetic nervous system. However, the chronic activation of hypothalamic–pituitary–adrenal and sympathetic nervous system axes during chronic or intense stress can lead...
OBJECTIVE: Pediatric obesity commonly co-exists with emotional and behavioral disorders, while disturbed Cortisol concentrations have been reported in both obese and chronically stressed individuals with anxiety and/or depression. We investigated the prevalence of internalizing and externalizing problems, reported by both parents and children, in a clinical population of obese children (OC) compared...
OBJECTIVE Hypovitaminosis D has been associated with adult as well as childhood obesity. Retinol-binding-protein-4 (RBP-4) and Neutrophil Gelatinase-associated Lipocalin (NGAL) are altered in obese individuals. The aim of this study was to examine circulating 25-(OH) Vitamin D (25-(OH) D) concentrations according to BMI and its associations with RBP-4 and NGAL in female children and adolescents. ...
Childhood obesity and its related comorbidities, such as dyslipidemia, arterial hypertension and impaired glucose metabolism, which constitute the Metabolic Syndrome, are associated with an increased risk for early onset endothelial dysfunction, atherosclerosis, and cardiovascular disease later in life. Genetic, epigenetic and developmental influences, such as maternal weight status during pregnancy,...
OBJECTIVE: To evaluate the effectiveness of active parental involvement in a lifestyle intervention for the management of childhood obesity. DESIGN: Forty-two overweight children (32 girls and 10 boys), aged 9.2±0.2 years and with percent overweight 39.8±2.7%, were randomly allocated either to a child-and-parent group (N = 23) or a child-alone group (N = 19). Both groups attended a 3-month multidisciplinary...
OBJECTIVE: Childhood obesity and the Metabolic Syndrome (MetS) are associated with an increased risk for early onset endothelial dysfunction and atherosclerosis. Placental growth factor (PlGF), a member of the vascular endothelial growth factor family, plays an important role in atherosclerosis by stimulating angiogenesis and atherogenic migration of monocytes/macrophages into the arterial wall. The...
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