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Traumatic brain injury (TBI) is the leading cause of death and disability in children, and can lead to long lasting functional impairment. Many factors influence outcome, but imaging studies examining effects of individual variables are limited by sample size. Roughly 20–40% of hospitalized TBI patients experience seizures, but not all of these patients go on to develop a recurrent seizure disorder...
Properties of the brain's structural networks can be analyzed by applying fiber-tracking techniques and network analysis to diffusion MRI. Here we applied exploratory factor analysis (EFA) to anatomical connectivity matrices, to identify brain networks whose properties predicted higher-order cognitive function. Using diffusion MRI scans from 104 healthy young adults, we computed connectivity matrices...
Diffusion imaging can map anatomical connectivity in the living brain, offering new insights into fundamental questions such as how the left and right brain hemispheres differ. Anatomical brain asymmetries are related to speech and language abilities, but less is known about left/right hemisphere differences in brain wiring. To assess this, we scanned 457 young adults (age 23.4±2.0 SD years) and 112...
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