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People with HIV are living longer as combination antiretroviral therapy (cART) becomes more widely available. However, even when plasma viral load is reduced to untraceable levels, chronic HIV infection is associated with neurological deficits and brain atrophy beyond that of normal aging. HIV is often marked by cortical and subcortical atrophy, but the integrity of the brain's white matter (WM) pathways...
Properties of the brain's structural networks can be analyzed by applying fiber-tracking techniques and network analysis to diffusion MRI. Here we applied exploratory factor analysis (EFA) to anatomical connectivity matrices, to identify brain networks whose properties predicted higher-order cognitive function. Using diffusion MRI scans from 104 healthy young adults, we computed connectivity matrices...
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