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Hypertension, or high blood pressure, is one of the most prevalent health problems in the world. Hypertension increases the risk of heart attack, heart failure, stroke, progressive atherosclerosis, and kidney disease. Accumulating body of evidence from epidemiological and clinical studies has demonstrated a connection between vitamin D deficiency or insufficiency and high blood pressure and cardiovascular...
The renin–angiotensin system (RAS) plays a central role in the regulation of blood pressure, volume and electrolyte homeostasis. Inappropriate activation of the RAS may lead to hypertension. Clinical and epidemiological studies have suggested a correlation between Vitamin D-deficiency and high blood pressure. Our recent studies demonstrate that Vitamin D is a potent endocrine suppressor of renin biosynthesis...
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