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The need to analyze increasingly large panels of biomolecules for biomedical research and clinical diagnostics has greatly stimulated the development of high-throughput screening technologies based on quantum dots. Herein, we describe recent advances in the synthesis of quantum-dot-encoded beads and control of their fluorescence signatures. Compared with commercial beads based on organic fluorophores,...
Multiplexed nanobarcodes have been prepared with quantum dots (QDs) and amphiphilic copolymers consisted of hydrocarbons and maleic anhydride groups. In homogenous solution, the QD-polymer complexes self-assemble into nanobeads with narrow size dispersity, which has been previously achieved only for micrometer-sized beads in the presence of solid supports. More than 250 QDs can be loaded into a nanobead...
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