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Objectives Betulin (BT) is an abundant triterpene found predominantly in the bark of Himalayan birch. It is difficult to deliver it in vivo because of its low aqueous solubility. We have therefore developed novel formulations of BT for improving its solubility, bioavailability and therapeutic efficacy. Results Poly-d,l-lactide nanovectors (PLA NVs) were synthesized using poly(vinyl alcohol) and...
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