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Increased oxidative stress and bronchial inflammation are important mechanisms in the pathophysiology of COPD.To investigate whether treatment with the inhaled corticosteroid fluticasone propionate (FP) or the anti-oxidative agent N-acetylcysteine (NAC) are effective in primary care patients.The study was a 3-year placebo-controlled randomised controlled trial preceded by a 3-month washout and 2-week...
Background: Spirometry is increasingly implemented in general practice, while the ability of general practitioners (GPs) to interpret flow-volume curves (F-V curves) has been questioned. Furthermore, the role of spirometry in the GPs decision-making process has barely been studied.Aim: To compare the achievements of trained GPs in spirometric diagnosis with an expert consensus panel (1) and to assess...
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