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Background Tuberculosis (TB) in children is neglected, mainly due to lack of sensitive diagnostic tools. Recently Xpert MTB/RIF assay has revolutionized the diagnostic field, but its usefulness in pediatric TB has not been reported from India and no report is available on its use on long term archived samples. Methods We recruited 130 pediatric patients with probable intrathoracic tuberculosis and...
The diagnosis of tuberculosis (TB) in childhood continues to be surrounded by considerable uncertainty, especially due to the difficulty in collecting sputum samples in children and the paucibacillary nature of childhood TB. Till date direct-smear microscopy, solid and liquid culture and chest radiography remain the cornerstones of diagnosis. But over the last decade significant changes have occurred...
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