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Background and aims Integrins such as α2β1, αIIbβ3, and αvβ3 have been suggested as key players for cancer development and progression. Several polymorphisms affecting these molecules, two in integrin α2 (ITGA2 807C>T and 1648G>A) and one in β3 (ITGB3 176T>C), influence their levels, structure, and possibly their function. To analyze the role of ITGA2 and ITGB3 polymorphisms for colorectal...
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