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Two rare jatropham lactam derivatives, named as fulvanines J−K (1‐2), together with six known pyrrole alkaloids, 5,5′‐oxydi(3‐methyl‐3‐pyrrolin‐2‐one) (3), (−)‐5‐hydroxy‐3‐methyl‐3‐pyrrolin‐2‐one (jatropham) (4), (±)‐5‐O‐methyljatropham (5), perlolyrine (6), butyl‐2‐formyl‐5‐(hydroxymethyl)‐1H‐pyrrole‐1‐butanoate (7), and hemerocallisamine II (8), were isolated from the flower of Hemerocallis fulva...
The abnormal uterine bleeding (AUB) is complex and usually leads to severe anemia. Melastomadodecandrum (MD) is clinically used for the treatment of metrorrhagia bleeding. The MD ellagitannins (MD‐ETs) had been evidenced being effective at hemorrhage, and exerts biological activities upon their metabolites including ellagic acid and urolithins. In this study, the blood‐permeated metabolites from theMD‐ETs...
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