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Nasopharyngeal carcinoma (NPC) is characterized by its highly invasive and metastatic features. Therefore, screening genetic biomarkers of NPC to achieve early diagnose would be of great value for NPC therapy. Single nucleotide polymorphisms in let-7 miRNA binding site in 3′ untranslated region of KRAS mRNA have been found to be associated with various cancer risks. In this study, we genotyped the...
Recently, single nucleotide polymorphisms in let-7 miRNA binding site in 3′ untranslated region (UTR) of KRAS mRNA have been found to be associated with the cancer risk. In this study, we genotyped the frequency of KRAS rs712 to test its effect on gastric cancer (GC) risk in a hospital-based case–control study in a Chinese population, with 181 histologically confirmed GC patients and 674 cancer-free...
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