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Dual-tracer PET imaging may improve overall lesion detectability due to different tracer kinetics. However, separating two tracers in the mixed acquired data is difficult because of unknown individual activity change over time. We proposed an effective and robust method to separate two tracers dynamically, by introducing joint Patlak and Logan analysis in dual-tracer PET imaging. Several patients...
We propose a novel method to directly estimate parametric images from listmode PET data for reversible tracers based on an inhomogeneous Poisson process model. We use a relative equilibrium graphical model, similar to the Logan plot, to linearize the problem. A static sinogram from time of tracer injection to the steady state is incorporated to improve the ill-conditioning of the estimation problem...
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