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Dehydroepiandrosterone sulphate is one of the most important neurosteroids. In the present paper, we studied the effect of dehydroepiandrosterone sulphate on persistent sodium currents and its mechanism and functional consequence with whole-cell patch clamp recording method combined with a pharmacological approach in the rat medial prefrontal cortex slices. The results showed that dehydroepiandrosterone...
Hypoxia-induced inhibition of Q i site of mitochondrial complex III under hypoxia has received attention, but its downstream pathways remain unclear. In this paper, we used Q i site inhibitor antimycin A to mimic the inhibition of the Q i site of mitochondrial complex III and studied the effects of the inhibition of this site on persistent sodium currents, transient sodium...
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