Search results for: Tong Yang

Items from 1 to 20 out of 340 results

article

CircCUL1 inhibits trophoblast cell migration and invasion and promotes cell autophagy by sponging hsa‐miR‐30e‐3p in fetal growth restriction via the ANXA1/PI3K/AKT axis

Tong Yang, Jianguo Hu, Lei Zhang, Li Liu, more

Journal of Biochemical and Molecular Toxicology > 38 > 7 > n/a - n/a

Fetal growth restriction (FGR) severely affects the health outcome of newborns and represents a major cause of perinatal morbidity. The precise involvement of circCULT1 in the progression of FGR remains unclear. We performed next‐generation sequencing and RT‐qPCR to identify differentially expressed circRNAs in placental tissues affected by FGR by comparing them with unaffected counterparts. Edu,...

article

P‐9.8: Design Method of LCoS Projection System Based on Multiplexing of Imaging and Illumination Optical Paths

Zeyuan Wu, Ximeng Wang, Tong Yang, Dewen Cheng

SID Symposium Digest of Technical Papers > 55 > S1 > 1185 - 1190

In this paper, we deduce and analyze the relationship between the back working distance and the design difficulty of the telecentric and reverse‐telephoto system in detail, and propose an innovative design idea for the LCoS projection system to solve this limitation. By employing optical path multiplexing in the imaging and illumination systems, the back working distance is reduced, leading to improved...

article

4‐2: Design of MLA‐based Integrated Projection System Using Radial Basis Function Mapping Method

Xilong Dai, Tong Yang, Dewen Cheng

SID Symposium Digest of Technical Papers > 55 > S1 > 36 - 44

In this paper, we present a design method for MLA‐based integrated projection imaging system. By combining ray tracing method and RBF (radial basis function) mapping method, both geometrical and optical information of the muti‐channel projection system are efficiently obtained. A comprehensive image processing pipeline is proposed to address the issues such as misalignment of sub‐projection‐images,...

article

Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia–reperfusion injury

Xiangyu Chen, Tong Yang, Yue Zhou, Zhigang Mei, more

CNS Neuroscience & Therapeutics > 30 > 4 > n/a - n/a

Objectives Astragaloside IV (AST IV) and ligustrazine (Lig), the main ingredients of Astragali Radix and Chuanxiong Rhizoma respectively, have demonstrated significant benefits in treatment of cerebral ischemia ‐reperfusion injury (CIRI); however, the mechanisms underlying its benificial effects remain unclear. SUMO‐1ylation and deSUMO‐2/3ylation of dynamin‐related protein 1 (Drp1) results in mitochondrial...

article

Cytoplasmic SIRT1 promotes paclitaxel resistance in ovarian carcinoma through increased formation and survival of polyploid giant cancer cells

Hong Xu, Shujun Zeng, Yingmei Wang, Tong Yang, more

The Journal of Pathology > 261 > 2 > 210 - 226

Therapeutic resistance is a notable cause of death in patients with ovarian carcinoma. Polyploid giant cancer cells (PGCCs), commonly arising in tumor tissues following chemotherapy, have recently been considered to contribute to drug resistance. As a type III deacetylase, Sirtuin1 (SIRT1) plays essential roles in the cell cycle, cellular senescence, and drug resistance. Accumulating evidence has...

article

P‐2.30: Design and Fabrication of an Optical Path Folding Pancake Virtual Reality Head‐mounted Display

Qichao Hou, Jiaping Sun, Yang Li, Tian Zhang, more

SID Symposium Digest of Technical Papers > 54 > S1 > 598 - 605

Metaverse has been going viral across the globe, and virtual reality head‐mounted displays (VR‐HMDs) as the basic infrastructure and entrance to cater to this evolution of social interaction are showing rapid development recently. Pancake optics based on optical path folding provides the feasibility of VR‐HMDs in the form of glasses and is wide recognition. The pancake system has become the current...

article

Postbuckling behavior and failure prediction of large‐size composite C‐beam under bending‐shear coupling load

Ziyu Zhao, Tong Yang, Fa Zhang, Pibo Ma

Polymer Composites > 44 > 7 > 4266 - 4278

In this article, a novel experimental device that combines bending and shearing was proposed to investigate the load‐bearing performance of large‐size C‐beam structures against bending‐shear buckling, allowing for the adjustment of bending‐shearing ratio. Three different bending‐shear coupling conditions were performed for test loading, and the strain gauges were carried out to detect the strain distribution...

article

Deep learning improves prediction of periodontal therapy effectiveness in Chinese patients

Ruiyang Wang, Ruixin Wang, Tong Yang, Jian Jiao, more

Journal of Periodontal Research > 58 > 3 > 520 - 528

The objective This study aims to propose a new model to predict the specific treatment effectiveness at site level by analyzing massive amounts of periodontal clinical data with deep learning methods. The background data discussing the present status of the field In light of the low accuracy of current tools, the proposed models cannot fully meet the needs of clinical effectiveness prediction and...

article

Precise Functionalization of a Multiple‐Resonance Framework: Constructing Narrowband Organic Electroluminescent Materials with External Quantum Efficiency over 40%

Qingyang Wang, Yincai Xu, Tong Yang, Jianan Xue, more

Advanced Materials > 35 > 3 > n/a - n/a

It is of important strategic significance to develop high‐efficiency narrowband organic electroluminescent materials that can be employed to fabricate ultrahigh‐definition displays with wide color gamut. This topic implies a great challenge to molecular design and synthesis, especially for the development of universality, diversity, scalability, and robustness of molecular architectonics. In this...

article

Alkaline media‐sensitive nanocarrier based on carboxylated cyclodextrin for targeted delivery of anti‐colon drug

Shuai Chen, Fang‐Dao Zhu, Bi‐Lian Li, Jian‐Mei Yang, more

Journal of Applied Polymer Science > 139 > 46 > n/a - n/a

The pH‐responsive nanoparticles are a promising drug‐carrier because they always showed sensitivity and specificity to the pH changes caused by the surrounding environment. Most of the therapeutic drugs are generally absorbed in the stomach and small intestine due to the pH‐responsive nanoparticles always release the cargos at acidic media, making them difficult to reach the lower part of the large...

article

Amino‐functionalized perylenediimide derivative with dual fluorescence emission for the detection of ascorbic acid in vivo and in vitro

Gui‐Qun Zhang, Kuan‐Neng Chi, Chao Yao, Tong Yang, more

Luminescence > 37 > 10 > 1741 - 1750

The rapid, sensitive, and selective detection of ascorbic acid (AA) is of significance in medical assays and diagnostics. In this work, a new aminoperylenediimide (APDI) derived ratiometric fluorescent probe based on the specific redox reaction of cobalt oxyhydroxide (CoOOH) and AA was constructed. APDI exhibited dual fluorescence emission peaks at 549 and 596 nm with an excitation wavelength of 494...

article

Modulated Synthesis of Self‐Standing Covalent Organic Framework Films

Yang Wang, Bei Guo, Tong Yang, Zhi‐Cong Zhang, more

Chemistry – A European Journal > 28 > 46 > n/a - n/a

The weak interaction of covalent organic framework (COF) nanoparticles makes the preparation of self‐standing COF films difficult. Herein, a modulated strategy for the facile synthesis of self‐standing COF films with good crystallinity and tunable thickness is reported. As compared with the non‐modulated approach, the modulated strategy changes the COF morphology from nanoparticles to nanofibers,...

article

Favorable effect of rivaroxaban against vascular dysfunction in diabetic mice by inhibiting NLRP3 inflammasome activation

Qing Li, Xin‐Tong Yang, Wei Wei, Xiang‐Peng Hu, more

Journal of Cellular Physiology > 237 > 8 > 3369 - 3380

Cardiovascular disease (CVD) is the leading cause of death in various complications of type 2 diabetes mellitus (T2DM). Rivaroxaban (Xarelto; Bayer), an oral direct factor Xa (FXa) inhibitor, prevents the activation of the coagulation cascade in CVD. Considering its anticoagulant and anti‐inflammatory effects, we assessed the hypothesis that rivaroxaban treatment may attenuate the vascular lesion...

article

L‐OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice

Hui‐Ling Jiang, Hui‐Hui Yang, Yu‐Biao Liu, Chen‐Yu Zhang, more

Journal of Cellular Physiology > 237 > 7 > 3030 - 3043

Necroptosis, a recently described form of programmed cell death, is the main way of alveolar epithelial cells (AECs) death in acute lung injury (ALI). While the mechanism of how to trigger necroptosis in AECs during ALI has been rarely evaluated. Long optic atrophy protein 1 (L‐OPA1) is a crucial mitochondrial inner membrane fusion protein, and its deficiency impairs mitochondrial function. This study...

article

Expansion of granulocytic myeloid‐derived suppressor cells in patients with severe fever with thrombocytopenia syndrome

Juan Du, Xiao‐Kun Li, Xue‐Fang Peng, Wen Xu, more

Journal of Medical Virology > 94 > 9 > 4329 - 4337

Severe fever with thrombocytopenia syndrome (SFTS), caused by novel bunyavirus (SFTSV), is a hemorrhagic fever with a high mortality rate of over 10%. We have previously shown that granulocytic myeloid‐derived suppressor cell (gMDSC) might affect arginine metabolism, which was associated with decreased platelet count and T lymphocyte dysfunction in this disease. The study was designed to investigate...

article

Well‐Posedness in Gevrey Function Space for 3D Prandtl Equations without Structural Assumption

Wei‐Xi Li, Nader Masmoudi, Tong Yang

Communications on Pure and Applied Mathematics > 75 > 8 > 1755 - 1797

We establish the well‐posedness in Gevrey function space with optimal class of regularity 2 for the three‐dimensional Prandtl system without any structural assumption. The proof combines in a novel way a new cancellation in the system with some of the old ideas to overcome the difficulty of the loss of derivatives in the system. This shows that the three‐dimensional instabilities in the system leading...

article

Accurate redox potentials for solvents in Li‐metal batteries and assessment of density functionals

Wenna Zhang, Tong Yang, Kristin Zhao, Xiaobin Liao, more

International Journal of Quantum Chemistry > 122 > 10 > n/a - n/a

The practical applications of Li metal batteries (LMBs) have been limited by the anodic instability which causes fatal problems including low Coulombic efficiency and short cycling lifespan. One way of addressing this issue is to develop new solvents with suitable redox potentials for electrolytes of LMBs. By using the recently developed Wuhan–Minnesota‐scaling method, the work has developed the Redox20...

article

Effects of hypoxia stress on digestive enzyme activities, intestinal structure and the expression of tight junction proteins coding genes in juvenile cobia (Rachycentron canadum)

Er‐Jun Yang, Jian‐Dong Zhang, Lin‐Tong Yang, Eric Amenyogbe, more

Aquaculture Research > 52 > 11 > 5630 - 5641

In this study, juvenile cobia fish (Rachycentron canadum) (body weight: 50.44 ± 2.78 g) were used as a study object to investigate the effects of hypoxia stress (dissolved oxygen: 3.15 ± 0.21 mg/L) on the activities of their digestive enzymes, intestinal morphology and relative expression of tight junction proteins coding genes. Under the experimental conditions, the juvenile cobia were given 28 days...

article

The association between cardiovascular risk burden and cognitive function amongst the old: a 9‐year longitudinal cohort study

Xiaomin Wu, Hualou Wang, Chong Chen, Ying Xiong, more

European Journal of Neurology > 28 > 9 > 2907 - 2912

Background and purpose Cardiovascular risk burden in midlife has been linked to cognitive decline in later life, but whether this association still exists in older cohorts is unclear. Methods The association between the cardiovascular risk score and cognitive function was investigated using 9‐year follow‐up data. The risk score algorithms were from the Chinese guidelines on the prevention and treatment...

article

A systematic meta‐analysis of immune signatures in patients with COVID‐19

Kun Liu, Tong Yang, Xue‐Fang Peng, Shou‐Ming Lv, more

Reviews in Medical Virology > 31 > 4 > n/a - n/a

Currently severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) transmission has been on the rise worldwide. Predicting outcome in COVID‐19 remains challenging, and the search for more robust predictors continues. We made a systematic meta‐analysis on the current literature from 1 January 2020 to 15 August 2020 that independently evaluated 32 circulatory immunological signatures that were...

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INFONA - science communication portal

Search results for: Tong Yang

CircCUL1 inhibits trophoblast cell migration and invasion and promotes cell autophagy by sponging hsa‐miR‐30e‐3p in fetal growth restriction via the ANXA1/PI3K/AKT axis

P‐9.8: Design Method of LCoS Projection System Based on Multiplexing of Imaging and Illumination Optical Paths

4‐2: Design of MLA‐based Integrated Projection System Using Radial Basis Function Mapping Method

Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia–reperfusion injury

Cytoplasmic SIRT1 promotes paclitaxel resistance in ovarian carcinoma through increased formation and survival of polyploid giant cancer cells

P‐2.30: Design and Fabrication of an Optical Path Folding Pancake Virtual Reality Head‐mounted Display

Postbuckling behavior and failure prediction of large‐size composite C‐beam under bending‐shear coupling load

Deep learning improves prediction of periodontal therapy effectiveness in Chinese patients

Precise Functionalization of a Multiple‐Resonance Framework: Constructing Narrowband Organic Electroluminescent Materials with External Quantum Efficiency over 40%

Alkaline media‐sensitive nanocarrier based on carboxylated cyclodextrin for targeted delivery of anti‐colon drug

Amino‐functionalized perylenediimide derivative with dual fluorescence emission for the detection of ascorbic acid in vivo and in vitro

Modulated Synthesis of Self‐Standing Covalent Organic Framework Films

Favorable effect of rivaroxaban against vascular dysfunction in diabetic mice by inhibiting NLRP3 inflammasome activation

L‐OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice

Expansion of granulocytic myeloid‐derived suppressor cells in patients with severe fever with thrombocytopenia syndrome

Well‐Posedness in Gevrey Function Space for 3D Prandtl Equations without Structural Assumption

Accurate redox potentials for solvents in Li‐metal batteries and assessment of density functionals

Effects of hypoxia stress on digestive enzyme activities, intestinal structure and the expression of tight junction proteins coding genes in juvenile cobia (Rachycentron canadum)

The association between cardiovascular risk burden and cognitive function amongst the old: a 9‐year longitudinal cohort study

A systematic meta‐analysis of immune signatures in patients with COVID‐19

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