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A porphyrin modified by glycine has been synthesized and developed as a near-infrared (NIR) fluorescence probe to detect tumor. Porphyrins’ longwavelength emission at ∼650nm can efficiently avoid the spectral crosstalk with Spontaneous fluorescence in the visible light region. A disulfide-based cyclic RGD peptide named iRGD c (CRGDKGPDC), a tumor homing peptide, harbors a cryptic C-end Rule (CendR)...
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