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HBsAg quantitation may be useful for managing patients with hepatitis B virus (HBV) infection.We explored the clinical implications of HBsAg quantitation for patients with HBsAg levels >250IU/ml (Abbott Diagnostics).Two hundred and thirty-three HBV-infected patients comprising 29 immune tolerance cases, 49 treatment-naïve HBeAg-positive chronic hepatitis B (CHB) cases, 91 inactive HBV carrier cases,...
Background: In the GLOBE trial, telbivudine demonstrated superior efficacy to lamivudine at 2 years in patients with chronic hepatitis B (CHB).
Aims: To investigate the long‐term efficacy and safety of telbivudine in the telbivudine‐treated cohort from the GLOBE trial.
Methods: Virological and biochemical responses were assessed in 213 HBeAg‐positive and 186 HBeAg‐negative CHB patients who continued...
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