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Osteopontin (OPN) promotes the migration and adhesion of vascular smooth muscle cells (VSMCs) through cell surface receptor, integrin β3. In order to elucidate the signaling pathway by which OPN is involved in neointimal formation, we focused on integrin β3-focal adhesion kinase (FAK) upon VSMC migration.The integrin β3 and FAK expression in VSMC and in neointima was detected by Western blot and immunohistochemistry...
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