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The examinations were conducted on hepatocvtes isolated by means of enzymatic method from the liver of three-month-old Wistar rats. The cells were incubated in medium with addition of theophylline and/or N-acetylcysteine. Significant changes in the activity of SOD, GPx, and GR in hepatocvtes incubated in the presence of the compounds in comparison with control cells demonstrated that theophylline...
The effect of L(+)ascorbic acid and/or sodium nitrate in nitric oxide production by hepatocytes in vitro was studied. It was demonstrated that the compounds added into an incubation medium stimulated nitric oxide production in hepatocytes. The highest concentration of nitric oxide was assayed after the incubation of the cells with sodium nitrate and L(+)ascorbic acid. It was found that the addition...
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