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Type 2 diabetes is characterized by agradual decline in insulin secretion in response to nutrient loads; hence, it is primarily a disorder of post-prandial glucose (PPG) regulation. However, physicians continue to rely on fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) to guide managementThe objectives of this article are to review current data on postprandial hyperglycemia and to...
While it is well established that overall glycemic control reduces the complications of diabetes, the role of fasting glycemia versus postprandial glycemia in the pathophysiology of diabetes and its complications, and the relative importance of these parameters as specific targets of therapy, remain controversial. Evidence that postprandial glucose (PPG) plays an independent, modifiable role in cardiovascular...
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