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The expression of human placental aromatase is transcriptionally regulated through the promoter region of exon 1a (I.1) of the gene. We examined the transcriptional regulation by using human choriocarcinoma-derived JEG-3 cells which also express aromatase mRNA transcribed under the control of the placenta-specific promoter of the exon 1a. Aromatase in the cells was induced by forskolin (cAMP) and...
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