The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
In the Quality-by-Design (QbD) paradigm for pharmaceutical processes, critical quality attributes (CQAs) must meet specifications for all possible realizations of critical process parameters (CPPs) within a design space. During the startup of such a process, it is desired to begin meeting CQA specifications as quickly as possible and then robustly guarantee that specifications will continue to be...
A commonly applied procedure in the pharmaceutical industry is to determine the maximum allowable set of uncertain parameters—called the design space—that guarantees that the product quality attributes obtained by a manufacturing process are within the specific limits. Design spaces in industry are constructed without considering the effects of process dynamics or feedback control, which results in...
This paper reviews the use of linear matrix inequalities (LMIs) and bilinear matrix inequalities (BMIs) in the formulation of many important problems in process control such as: control structure selection, robust controller analysis and design, parameter estimation, and optimal design of experiments.
Partial differential equations (PDEs) pose a challenge for control engineers, both in terms of theory and computational requirements. PDEs are usually approximated by ordinary differential or partial difference equations via the finite difference method, resulting in a high-dimensional state-space system. The obtained system matrix is often symmetric, which allows this high-dimensional system to be...
Polynomial-time algorithms are proposed for computing tight ellipsoidal bounds on the state trajectories of discrete-time linear systems with time-varying or time-invariant linear fractional parameter uncertainties and ellipsoidal uncertainty in the initial state. The approach employs linear matrix inequalities to determine an initial estimate of the ellipsoid, which is improved by the subsequent...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.