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Whilst looking for components involved in retinol metabolism in secreting mammary gland cells, a 12 kDa Protein was isolated. This protein had bound a ligand with characteristics of retinol. N-Terminal sequencing and amino acid analysis showed that this protein is highly homologous with an α-sl-casein fragment. No ligand was found for β-lactoglobulin, previously thought to be involved in retinol metabolism.
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