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Rationale. Dopamine D1 receptor agonists and antagonists attenuate reinstatement of cocaine seeking in a non-human primate model of relapse. The mechanisms by which these different classes of D1 receptor drugs produce these similar effects on cocaine seeking are unknown. Objectives. This study investigated how D1 receptor agonists and antagonists alter the shape and position of the doseresponse function...
Rationale Dopamine D1 receptor agonists and antagonists attenuate reinstatement of cocaine seeking in a non-human primate model of relapse. The mechanisms by which these different classes of D1 receptor drugs produce these similar effects on cocaine seeking are unknown. Objectives This study investigated how D1 receptor agonists and antagonists alter the shape and position of the dose–response function...
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