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Background Pancreatic neuropathy in chronic pancreatitis (CP) and pancreatic cancer (PCa) is characterized by pancreatic neuropathy, i.e. increased neural density and hypertrophy, which are associated with neuropathic pain. To better understand the mechanism of these neuropathic alterations, we aimed at achieving an in‐vitro simulation of the intrapancreatic neuroplasticity.
Methods Dissociated...
Summary BACKGROUND: Chronic pancreatitis (CP) is a recurrent illness with complete destruction of the pancreatic gland in end-stage disease. Alcohol consumption is the most common cause of pancreatitis in Western countries, but hereditary factors, mechanical obstruction and autoimmune processes are also critical contributing factors. Pain and functional disorders characterize this illness, which is...
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