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Fibroblast activation protein (FAPα) is a member of the cell surface dipeptidyl peptidase (DPP) family of serine proteases. In its dimer form, FAPα exhibits gelatinase, collagenase, and DPP activity in vitro. Reactive fibroblasts in healing wounds and stromal fibroblasts associated with epithelial tumors express FAPα. Idiopathic pulmonary fibrosis (IPF) is a disease of the lung characterized by progressive...
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