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Aims/hypothesis. This study aimed to examine brain energy metabolism during moderate insulin-induced hypoglycaemia in Type 1 diabetic patients and healthy volunteers. Methods. Type 1 diabetic patients (mean diabetes duration 132.5 years; HbA1c 6.80.3%) and matched controls were studied before, during (0120min) and after (120240min) hypoglycaemic (~3.0mmol/l) hyperinsulinaemic (1.5mUkg1min1) clamp...
Aims/hypothesis This study aimed to examine brain energy metabolism during moderate insulin-induced hypoglycaemia in Type 1 diabetic patients and healthy volunteers. Methods Type 1 diabetic patients (mean diabetes duration 13±2.5 years; HbA1c 6.8±0.3%) and matched controls were studied before, during (0–120 min) and after (120–240 min) hypoglycaemic (~3.0 mmol/l) hyperinsulinaemic (1.5 mU·kg−1·min...
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