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Purpose The aim of the study was to assess the clinical activity and toxicity of oxaliplatin and leucovorin in combination with bolus and continuous infusional 5-fluorouracil administered every 2 weeks (modified FOLFOX-6 regimen) to patients with adenocarcinoma of an unknown primary site (ACUP). Methods Previously untreated ACUP patients were treated with oxaliplatin (100 mg/m2) and leucovorin (200 mg/m...
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