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Kinetic analysis can be applied both to dynamic PET and dynamic contrast enhanced (DCE) MRI data. We have investigated the potential of MRI-constrained PET kinetic modeling using simulated [ ]2-FDG data for skeletal muscle. The volume of distribution, , for the extra-vascular extra-cellular space (EES) is the link between the two models: It can be estimated by DCE-MRI, and then...
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