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Background:Insulin and insulin-like growth factors can stimulateproliferation of colorectal cells. High intake of refined carbohydrates andmarkers of insulin resistance are associated with colorectal cancer. To testthe insulin/colon cancer hypothesis, we determined whether the dietaryglycemic index and the glycemic load are associated with colorectal cancerrisk. Design:A case-control study on colorectal...
A case-control study was conducted between 1992 and 1996 in six Italian areas. It included 537 women with colon cancer, 291 women with rectal cancer and 2081 control women in hospital for acute conditions, unrelated to hormonal or gynaecological diseases. A higher age at menopause was associated with increased colon cancer risk (odds ratio (OR) for ≥ 53 years compared with < 50 years = 1.39,...
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