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We report here that, clofazimine (CFZ) treatment (0.1-10 μM) led to inhibition of in vitro proliferation of hepatocellular carcinoma (HCC) cell lines Hep3-β, HuH-7, HepG2, SKHEP-1, PLC/PRF-5 and Novikoff. A 24 h exposure of human HuH-7 cells to various concentrations of CFZ dissolved in lipiodol (CFZ-L 10-160 μM), followed by 4 days treatment with medium alone, also led to dose-dependant inhibition...
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