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Background: Interferon (IFN) retreatment for hepatitis C virus (HCV) relapsers has been effective under some conditions. We conducted a randomized, controlled trial of IFN β retreatment for HCV relapsers after IFN α. Patients and methods: We gave IFN β 6MIU therapy to 43 patients who had relapse of HCV after the 24 weeks IFN α monotherapy. The 43 patients were randomly assigned to two groups: Group...
Objectives: To investigate the efficacy of prolonged IFN retreatment for 3 years in chronic hepatitis C patients with high viral load and IFN treatment-resistant genotype 1b. Patients and methods: The study was conducted in 12 patients, not HCV RNA-negative after completion of the initial treatment. Retreatment consisted of administration of 6 million international units (MIU) of natural interferon-α,...
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