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The interaction between barrier-to-autointegration factor dimer (BAF2) and LEM domain of emerin (Em LEM ) was studied by molecular simulation methods. Nonspecific fragment of double-strand DNA molecule was docked with each chain of BAF2 by ZDOCK program. The model of DNA2:BAF2:Em LEM was thus constructed. The mutant Gly25Glu of BAF2 was manually constructed to explore the detailed...
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