The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Purpose
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. It is a highly aggressive cancer in which nearly 50% of patients die from liver metastasis. UM patients can be divided into 3 groups based on their genetic profile and disease free survival; the low risk, intermediate risk and high risk tumours. Recently, we have shown that high risk patients can be identified...
Purpose
Rationale: In uveal melanoma (UM) non‐random chromosomal aberrations occur and correspond to patients’ prognosis. Mutations in UM specific genes, such as BAP1, SF3B1 and EIF1AX are also used to predict survival. Aim of this study is to identify these mutations corresponding to a specific chromosomal signature in UM.
Methods
For 277 UM patients SNP array data (n =214) and/or conventional...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.