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For high-risk low-grade gliomas (LGGs), adjuvant radiotherapy (RT) with procarbazine/lomustine/vincristine (PCV) chemotherapy increases overall survival (OS) over RT alone. However, in practice, temozolomide (TMZ) is often used instead of PCV. Using the National Cancer Data Base (NCDB), we provide the first investigation of practice patterns and outcomes of chemoradiotherapy with single-agent chemotherapy...
BACKGROUNDThe objective of this study was to evaluate local control and patterns of failure in pediatric patients with low‐grade glioma (LGG) who received treatment with intensity‐modulated radiation therapy (IMRT).
METHODSIn total, 39 children received IMRT after incomplete resection or disease progression. Three methods of target delineation were used. The first was to delineate the gross tumor...
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