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With colorful and high-contrast images, fluorescence imaging has long been a powerful tool used to confirm existing hypotheses or ideas suggested by other experimental approaches.Since data acquired by fluorescence imaging contain numerical values for spatio-temporal information as well as fluorescence intensities, quantitative fluorescence imaging is considered a robust tool that can provide novel...
Mechanical loading on the bone is sensed by osteocytes. Sclerostin is a molecule secreted by osteocytes that is downregulated by mechanical loading; therefore, its expression level is a potent sensor that indicates the spatial transduction of biomechanical properties in bone. This study applied macroconfocal microscopy to observe the spatial response of alveolar bone to orthodontic forces after immunofluorescence...
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