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Abstract Effects of the intravenous anaesthetic ketamine on the desipramine-sensitive noradrenaline transporter (NAT) were examined in cultured bovine adrenal medullary cells and in transfected Xenopus laevis oocytes expressing the bovine NAT (bNAT). Incubation (13 h) of adrenal medullary cells with ketamine (10300 M) caused an increase in appearance of catecholamines in culture medium. Ketamine (101000...
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