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Protein kinase CK2 (CK2) is highly expressed in rat forebrain where its function is not well understood. Subcellular distribution studies showed that the catalytic subunit of CK2 (CK2α) was enriched in postsynaptic densities (PSDs) by 68%. We studied the putative role of CK2 activity on N-methyl-d-aspartate receptor (NMDAR) function using isolated, patch-clamped PSDs in the presence of 2mM extracellular...
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