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Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti-angiogenic potential, we have investigated whether Sema3f can be used to protect against subretinal neovascularization in two mouse models. Both in the very...
Aims: The aim of the present study was to investigate the expression of amyloid-β peptide 42 (A β -42) in retinal ganglion cells in postnatal rats. Sprague-Dawley rats were divided into 7 experimental groups: 3, 6, 13, 15, 25, 60, and 90 day postnatal groups. Rats from 15 and 25 day postnatal groups were further divided into light-exposure and non light-exposure group. Cryosections or flat-mounted...
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