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Vonoprazan Fumarate (TAK-438F) is a new and effective drug approved in Japan in 2014 for treatment and prevention of acid-related diseases (ARDs), which exhibits many advantages compared with traditional proton-pump inhibitors (PPIs). However, the clinical applications of TAK0-438F suffers limitation due to the lack of injection dosage form. Efforts to overcome this limitation lead to the systhesis...
Lysimachia capillipes Hemsl (Primulaceae), a folk medicinal plant in China, showed significant anti‐tumor activities in vivo and in vitro. Capilliposide B (LC‐B) and capilliposide C (LC‐C) are the main bioactive components in this plant. To explore their tissue distribution, a reliable bioanalytical method for the quantification of LC‐B, LC‐C and their bioactive metabolite, capilliposide A (LC‐A),...
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