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Objectives: To study motor cortex (M1) excitability and the effect of subthreshold transcranial magnetic stimulation (TMS) in patients with cerebellar degeneration and normals performing a reaction time (RT) task.Methods: Time to wrist flexion after a visual go-signal was measured. TMS was always delivered at 90% of resting motor evoked potential (MEP) threshold. In one experiment, test TMS was delivered...
Patients who have suffered hemiplegia from stroke may have some spontaneous recovery that is likely due to reorganization within the cerebral cortex. Understanding this physiology should be useful in devising ways to help patients have better improvement. Techniques, such as transcranial magnetic stimulation and neuroimaging with positron emission tomography, can be used to demonstrate the organization...
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